Publications

Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy

Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments

Structural basis of the filamin A actin-binding domain interaction with F-actin

The actin filament twist changes abruptly at boundaries between bare and cofilin-decorated segments

Cryo-electron microscopy structures of pyrene-labeled ADP-P i- and ADP-actin filaments

Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides

Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase

Structures of a RAG-like transposase during cut-and-paste transposition

Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme

Symmetrical organization of proteins under docked synaptic vesicles

Symmetrical arrangement of proteins under release-ready vesicles in presynaptic terminals

Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release

High-resolution view of the type III secretion export apparatus in situ reveals membrane remodeling and a secretion pathway

A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion

Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers

Structure of Geobacter pili reveals secretory rather than nanowire behaviour

Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex

Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes

Structural basis of antagonism of human APOBEC3F by HIV-1 Vif

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617

Cryo-EM structures of Escherichia coli cytochrome bo 3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site

Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism

Cryo-EM structure of an active central apparatus

A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi

Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography

Structural dynamics of bacteriophage P22 infection initiation revealed by cryo-electron tomography

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

Molecular mechanism for rotational switching of the bacterial flagellar motor

FlhF regulates the number and configuration of periplasmic flagella in Borrelia burgdorferi

BB0326 is responsible for the formation of periplasmic flagellar collar and the assembly of the stator complex in Borrelia burgdorferi

Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coli

The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching

The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation

FliL ring enhances the function of periplasmic flagella

Composition and Biophysical Properties of the Sorting Platform Pods in the Shigella Type III Secretion System

In situ architecture of the lipid transport protein VPS13C at ER–lysosome membrane contacts

A phase-separated nuclear GBPL circuit controls immunity in plants

A human apolipoprotein L with detergent-like activity kills intracellular pathogens

Cryo-EM Structure of Monomeric Photosystem II from Synechocystis sp. PCC 6803 Lacking the Water-Oxidation Complex

High-resolution cryo-electron microscopy structure of photosystem II from the mesophilic cyanobacterium, Synechocystis sp. PCC 6803

Single particle cryo-EM structure of the outer hair cell motor protein prestin

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern