Publications

Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy (2020)

Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments(2020)

Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex (2024)

Structural basis of the filamin A actin-binding domain interaction with F-actin(2018)

The actin filament twist changes abruptly at boundaries between bare and cofilin-decorated segments(2018)

Cryo-electron microscopy structures of pyrene-labeled ADP-P i- and ADP-actin filaments(2020)

Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides(2019)

Mechanism of actin filament branch formation by Arp2/3 complex revealed by a high-resolution cryo-EM structureof the branch junction (2022)

Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase(2020)

Structures of a RAG-like transposase during cut-and-paste transposition(2019)

Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme(2021)

Structural visualization of transcription activated by a multidrug-sensing MerR family regulator (2021)

Symmetrical organization of proteins under docked synaptic vesicles(2019)

Symmetrical arrangement of proteins under release-ready vesicles in presynaptic terminals(2021)

Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release(2022)

High-resolution view of the type III secretion export apparatus in situ reveals membrane remodeling and a secretion pathway(2019)

A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion(2019)

Cryo-EM structure of the needle filament tip complex of the Salmonella type III secretion injectisome (2021)

Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers(2019)

Structure of Geobacter pili reveals secretory rather than nanowire behaviour(2021)

Electric field stimulates production of highly conductive microbial OmcZ nanowires (2020)

Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex(2020)

Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes(2020)

Structural basis of antagonism of human APOBEC3F by HIV-1 Vif(2019)

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA(2020)

Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617(2022)

Structural basis for recruitment of host CypA and E3 ubiquitin ligase by maedi-visna virus Vif (2023)

Cryo-EM structures of Escherichia coli cytochrome bo 3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site(2021)

Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism(2021)

Cryo-EM structure of an active central apparatus(2022)

Multi-curve fitting and tubulin-lattice signal removal for structure determination of large microtubule-based motors (2022)

LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility (2023)

Cryo-EM reveals how the mastigoneme assembles and responds to environmental signal changes (2023)

Structures of the CcmABCD heme release complex at multiple states (2022)

A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi(2021)

Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography(2018)

Structural dynamics of bacteriophage P22 infection initiation revealed by cryo-electron tomography(2019)

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles(2020)

Molecular mechanism for rotational switching of the bacterial flagellar motor(2020)

FlhF regulates the number and configuration of periplasmic flagella in Borrelia burgdorferi(2020)

BB0326 is responsible for the formation of periplasmic flagellar collar and the assembly of the stator complex in Borrelia burgdorferi(2020)

Outer membrane vesicles and the outer membrane protein OmpU govern Vibrio cholerae biofilm matrix assembly (2024)

Anti-s28 Factor FlgM Regulates Flagellin Gene Expression and Flagellar Polarity of Treponema denticola (2023)

Transcriptome of Epibiont Saccharibacteria Nanosynbacter lyticus Strain TM7x During the Establishment of Symbiosis (2022)

BB0259 Encompasses a Peptidoglycan Lytic Enzyme Function for Proper Assembly of Periplasmic Flagella in Borrelia burgdorferi (2021)

Characterization of the Flagellar Collar Reveals Structural Plasticity Essential for Spirochete Motility (2021)

Transcriptional and functional characterizations of multiple flagellin genes in spirochetes (2022)

A mammalian system for high-resolution imaging of intact cells by cryo-electron tomography (2021)

A pleiotropic role of sialidase in the pathogenicity of Porphyromonas gingivalis (2024)

Bacterial flagella hijack type IV pili proteins to control motility (2024)

FlgV forms a flagellar motor ring that is required for optimal motility of Helicobacter pylori (2023)

Ice nucleation proteins self-assemble into large fibres to trigger freezing at near 0 °C (2023)

Diacylglycerol-dependent hexamers of the SNARE-assembling chaperone Munc13-1 cooperatively bind vesicles (2023)

An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria (2022)

A Tripartite Efflux System Affects Flagellum Stability in Helicobacter pylori (2022)

High-Resolution Structural Analysis of Dyneins by Cryo-electron Microscopy (2023)

Role of the major determinant of polar flagellation FlhG in the endoflagella- containing spirochete Leptospira (2021)

Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coli(2021)

The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching(2020)

The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation(2022)

FliL ring enhances the function of periplasmic flagella(2022)

Composition and Biophysical Properties of the Sorting Platform Pods in the Shigella Type III Secretion System(2021)

Cryo-EM structures of prefusion SIV envelope trimer (2022)

Exploitation of a Bacterium-Encoded Lytic Transglycosylase by a Human Oral Lytic Phage To Facilitate Infection (2022)

Developmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System (2022)

Identification and Characterization of the Alternative σ28 Factor in Treponema denticola (2022)

Structure of mavacamten-free human cardiac thick filaments within the sarcomere by cryoelectron tomography (2024)

Bacteria require phase separation for fitness in the mammalian gut (2023)

Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity (2023)

Parkinson’s disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella (2023)

In situ architecture of the lipid transport protein VPS13C at ER–lysosome membrane contacts(2022)

A phase-separated nuclear GBPL circuit controls immunity in plants(2021)

A human apolipoprotein L with detergent-like activity kills intracellular pathogens(2021)

Native architecture of a human GBP1 defense complex for cell-autonomous immunity to infection (2024)

Cryo-EM Structure of Monomeric Photosystem II from Synechocystis sp. PCC 6803 Lacking the Water-Oxidation Complex(2020)

High-resolution cryo-electron microscopy structure of photosystem II from the mesophilic cyanobacterium, Synechocystis sp. PCC 6803(2021)

Helical allophycocyanin nanotubes absorb far-red light in a thermophilic cyanobacterium (2023)

Structure of a dimeric photosystem II complex from a cyanobacterium acclimated to far-red light (2023)

Single particle cryo-EM structure of the outer hair cell motor protein prestin(2022)

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern(2022)

HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes (2023)

Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli (2022)

Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention (2023)

A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin (2023)

Structures of a mobile intron retroelement poised to attack its structured DNA target (2022)

The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands (2022)

A protocol for capturing RNA-sensing innate immune receptors in multiple conformations by single-particle cryo-EM (2023)

Structural insights into intron catalysis and dynamics during splicing (2023)

Structural insights into the mechanism of the sodium/iodide symporter (2022)

Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy (2020)

Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain (2020)

The molecular basis of sugar detection by an insect taste receptor (2024)

A mitochondrial megachannel resides in monomeric F1FO ATP synthase (2019)

Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism (2023)

How to correct relative voxel scale factors for calculations of vector-difference Fourier maps in cryo-EM (2022)