The instruments in the Yale CryoEM Resource (YCR) are housed at three sites: West Campus, Sterling Hall of Medicine (SHM), and Science Hill. They represent a substantial investment and resource for the Yale research community. To ensure that these resources are available to all interested investigators and are performing at their optimum level with a minimum of down-time, the Yale CryoEM Resource staff and Faculty Advisory Committee have established the YCR Policies and will periodically review and update the polices.
Acknowledgement of the Yale CryoEM Resource in publications: considerable and continued funding is essential for the YCR to provide high end support to the researchers with subsidized fees. In order to maintain this level of support it is critical that the YCR and its funding are acknowledged in publications. Therefore, publications that result from using the Yale CryoEM Resource are required to acknowledge the YCR and the grants, e.g., by adding a text similar to the following to their Acknowledgements: (1) “Cryo-EM data were collected at the Yale CryoEM Resource that is funded in part by the NIH grant S10OD023603.” if the YSB Glacios is used; (2) “Cryo-EM data were collected at the Yale CryoEM Resource.” for the use of all instruments other than YSB Glacios.
Please find the Yale organization-wide policies below.
Yale credentials are required to open the documents below.
- Access policy and rate
- Get started as a Yale internal user
- EM training request form (an example of the form)
- Talos L120C or T12 access request form (an example of the form)
- Glacios access request form (an example of the form)
- Titan Krios access request form (an example of the form)
Rates
Rates for internal users are available in the Access Policy and rate document.
- External user fees
| Instrument, Service, or Consumables | Location | External Academic | External For-Profit |
| Talos L120C | YSB | $115/hr | $240/hr |
| T12 | SHM | $115/hr | $240/hr |
| Glacios | YSB, SHM | $150/hr or $1800/day | $300/hr or $3600/day |
| Krios G2§ | WC | $2900/day | $5800/day |
| Vitrobot | YSB, SHM, WC | $135/hr | $160/hr |
| Chameleon | SHM | $190/hr | $320/hr |
| Plasma Cleaner | YSB, SHM | $150/hr | $200/hr |
| Carbon Coating | YSB, SHM | $145/hr | $160/hr |
| Negative staining EM training§ | YSB, SHM | $1820 flat fee | $3000 flat fee |
| Staff Support or Training | YSB, SHM, WC | $125/hr | $160/hr |
| Auto-grid ring and C-clip | YSB, SHM, WC | $28/set | $33/set |
| Autogrid box | YSB, SHM, WC | $20/each | $25/each |
| Chameleon grid | SHM | $30/each | $36/each |
§ Staff support included. No extra staff fee.
Location code: SHM (Sterling Hall of Medicine, a.k.a. Yale School of Medicine CCMI, at 333 Cedar Street), YSB (Yale Science Building at 260 Whitney Ave), WC (West Campus in West Haven).
Interested customers may contact staff at individual locations for technical consultation. We’ll forward you to the administrative staff for formal contract negotiation. The general process of becoming an external user is as follows: