User guidelines

workflow

The typical workflow for single particle projects.

A range of instruments is available to users to support research at different stages of their projects. Preliminary evaluation is performed utilizing the Talos L120C or T12 using negative staining EM. CryoEM sample optimization and data collection may be performed at Glacios equipped with a K3 direct detector. The Talos L120C microscope can be used for both negative staining EM and CryoEM sample optimization. The Titan Krios should be primarily used for large-scale data collection on optimized samples.

Training programs for beginners are provided at Yale School of Medicine and Science Hill sites.

Yale credentials are required to open the documents marked with *

Computational needs are supported by Center for Research Computing. Please follow their guidelines and instructions.

You can subscribe to the Cryoem-journalclub mailing list to receive updates and announcements. 

1. Go to this link:

https://mailman.yale.edu/mailman/listinfo/cryoem-journalclub

2. Fill in the top box on the page, your email address. Nothing else required.

3. Click Subscribe.

In addition, you can subscribe to the YSM_Structural_Biology_Seminar_Series mailing list by contacting titus.boggon@yale.edu

https://mailman.yale.edu/pipermail/ysm_structural_biology_seminar_serie…

Prospective external users may find the general process as follows: