NIH has established multiple national cryo-EM service centers to provide access to the technology and is supporting the development of cryo-EM training curricula to build a skilled workforce.
All three centers accept external proposals to use their resources. A key feature of these centers is that the access (including screening and training) is proposal-based and free of charge.
New Cryo-ET centers are accepting applications.
Additional free-of-charge Titan Krios access opportunities:
NCI provides access to Titan Krios to projects that are relevant in cancer research.
BNL Laboratory for Biomolecular Structure offers access opportunities similar to national centers.
MEDIC is a cryoEM facility based at UCLA David Geffen School of Medicine dedicated to MicroED technology development and structure solution.